Tropical Sprue — Its Aetiology and Pathogenesis

Tropical Sprue

of Tropical Diseases Tropical Sprue

One of the more mysterious and still rather poorly understood diseases seen in the tropical regions of the world is Tropical Sprue (TS). TS is a clinical syndrome with an unknown etiology typically characterized by an acquired chronic diarrheal illness, small bowel mucosal abnormalities and malabsorption resulting in nutritional deficiencies and weight loss [1]. These are vague symptoms which c...

Dysgammaglobulinaemia in tropical sprue.

Study of immunoglobulin levels in 16 Indian control subjects showed that, compared with a Danish control series, they had a significantly higher mean level of IgG, but not of IgA or IgM. By contrast, the IgG levels in eight patients with tropical sprue were decreased or low normal in six cases and raised in only one case. Two patients with tropical sprue had agamma-A-globulinaemia.Turnover stud...

Tropical sprue: revisited.

OBJECTIVE To review the experience of patients presenting with clinical manifestations of tropical sprue and assess their diagnosis and management, response to treatment and follow up. METHODS This single center retrospective descriptive study was done at Shifa International Hospital, Islamabad from January 1994 to January 2003. All patients who presented with diarrhea, anorexia, weight loss ...

Tropical Sprue Presenting with Dementia

Celiac and Tropical Sprue are malabsorptive diseases with similar clinical manifestations and histological findings. While, Celiac sprue is a known cause of malabsorption in the Western world, Tropical sprue is relatively uncommon and often overlooked by the medical community. Misdiagnosis can result in delay of adequate treatment in a patient with Tropical Sprue. We present a patient with a Tr...